Population genetic study of the brain-derived neurotrophic factor (BDNF) gene
نویسندگان
چکیده
منابع مشابه
The Pattern of Brain-Derived Neurotrophic Factor Gene Expression in the Hippocampus of Diabetic Rats
Objective(s) The aim of this study was to evaluate the effects of regular exercise in preventing diabetes complication in the hippocampus of streptozotocin (STZ)-induced diabetic rat. Materials and Methods A total of 48 male wistar rats were divided into four groups (control, control exercise, diabetic and diabetic exercise). Diabetes was induced by injection of single dose of STZ. Exercise ...
متن کاملFamily-based study of brain-derived neurotrophic factor (BDNF) gene polymorphism in alcohol dependence.
Brain-derived neurotrophic factor (BDNF) belongs to a family of proteins related to the nerve growth factor family, which are responsible for the proliferation, survival and differentiation of neurons. BDNF is thought to be involved in the pathogenesis of bipolar disorder, schizophrenia, eating disorders and addiction. We hypothesize that a functionally relevant polymorphism of the BDNF gene pr...
متن کاملBioinformatics Study of the Effect of Brain-derived Neurogenic Factor (BDNF) on Gene Expression in SH-SY5Y Cell Line
Introduction: Considering the importance of the evaluation and identification of BDNF protective pathways, this study was conducted to analyze the expression rate of genes registered in the NCBI database to identify the genes expressed in SH-SY5Y cell line due to BDNF protection and oxidative stress and also to identify the protective pathways of BDNF. Method: In this study, bioinformatics and ...
متن کاملBioinformatics Study of the Effect of Brain-derived Neurogenic Factor (BDNF) on Gene Expression in SH-SY5Y Cell Line
Introduction: Considering the importance of the evaluation and identification of BDNF protective pathways, this study was conducted to analyze the expression rate of genes registered in the NCBI database to identify the genes expressed in SH-SY5Y cell line due to BDNF protection and oxidative stress and also to identify the protective pathways of BDNF. Method: In this study, bioinformatics and ...
متن کاملBrain-derived neurotrophic factor (BDNF) gene and rapid-cycling bipolar disorder: family-based association study.
BACKGROUND We have previously reported the Val66Met and GT(n) repeat polymorphisms of the brain-derived neurotrophic factor (BDNF) gene to be associated with bipolar disorder. However, these findings have not been replicated consistently. AIMS To dissect the association of the BDNF gene with bipolar disorder by examining additional markers at the DNA level and by testing the illness categorie...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 2009
ISSN: 1359-4184,1476-5578
DOI: 10.1038/mp.2009.24